Chemical modification of proteins to improve...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 1/107 (2006.01) A61K 38/17 (2006.01) A61K 47/48 (2006.01) C07K 14/53 (2006.01) C07K 14/535 (2006.01) C07K 14/575 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2298864

The present invention broadly relates to chemical modification of biologically active proteins or analogs thereof. More spcecifically, the present invention describes novel methods for site-specific chemical modification of various proteins, and resultant compositions having improved biocompatibility and bioactivity.

La présente invention concerne d'une manière générale la modification chimique de protéines actives biologiquement ou d'analogues de celles-ci. Plus spécifiquement, la présente invention concerne de nouveaux procédés de modification chimique spécifique à un site de diverses protéines, ainsi que des compositions résultantes présentant une biocompatibilité et une bioactivité améliorées.

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