Chemokine receptor binding compounds

Details Chemokine receptor binding compounds Chemokine receptor binding compounds

A - Human Necessities

61

K

A61K 31/445 (2006.01) A61K 31/505 (2006.01) A61K 31/535 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 405/06 (2006.01) C07D 405/12 (2006.01) C07D 413/06 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2548393

The present invention relates to chemokine receptor binding compounds, pharmaceutical compositions and their use. More specifically, the present invention relates to modulators of chemokine receptor activity, preferably modulators of CCR5. These compounds demonstrate protective effects against infection of target cells by a human immunodeficiency virus (HIV).

L'invention concerne des composés de liaison aux récepteurs de la chemokine, des compositions pharmaceutiques et leur utilisation. L'invention concerne, plus spécifiquement, des modulateurs de l'activité des récepteurs de la chemokine, de préférence, des modulateurs de CCR5. Lesdits composés possèdent des effets protecteurs contre une infection de cellules cibles par le virus de l'immunodéficience humaine (VIH).

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