C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/135 (2006.01) A61K 39/155 (2006.01) A61P 31/14 (2006.01) C12N 15/45 (2006.01)
Patent
CA 2684578
Chimeric respiratory syncytial virus (RSV) polypeptide antigens are provided. The disclosed polypeptides include in an N-terminal to C-terminal direction: a first F protein polypeptide domain; a G protein polyeptpide domain; and a second F protein polypeptide domain. The disclosure also provides nucleic acids that encode, and pharmaceutical compositions that contain, the chimeric RSV polypeptides, as well as methods for their production and use.
La présente invention concerne des antigènes polypeptidiques chimériques du virus respiratoire syncytial (RSV). Les polypeptides décrits comprennent, dans un sens N-terminal à C-terminal : un premier domaine polypeptidique de protéine F ; un domaine polypeptidique de protéine G ; et un second domaine polypeptidique de protéine F. La description concerne également des acides nucléiques qui codent pour, et des compositions pharmaceutiques qui contiennent, les polypeptides chimériques du RSV, ainsi que des procédés pour leur production et leur utilisation.
Blais Normand
Burt David S.
Cyr Sonia L.
Martin Denis L.
Rheault Patrick
Gowling Lafleur Henderson Llp
Id Biomedical Corporation Of Quebec
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