Chiral stationary phases based on derivatives of...

B - Operations – Transporting – 01 – J

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B01J 20/32 (2006.01) B01D 15/08 (2006.01) G01N 30/48 (2000.01)

Patent

CA 2440639

The invention describes new chiral stationary phases containing a 4-amino-3,5- dinitrobenzoic unit modified with chiral groups and spacer groups. The invention includes the process for the perparation of said stationary phases starting from 4-halogenated derivative of 3,5-dinitrobenzoic acid, chiral selectors obtainable as intermediates in the aforesaid process, and the use of the chiral stationary phases in the separation of enantiomers.

L'invention concerne de nouvelles phases chirales stationnaires contenant une unité 4-amino-3,5-dinitrobenzoïque modifiée par des groupes chiraux et des groupes intercalaires. L'invention concerne également le procédé de préparation de ces phases stationnaires à partir de dérivés 4-halogénés d'acide 3,5-dinitrobenzoïque, des sélecteurs chiraux pouvant être obtenus comme intermédiaires dans le procédé susmentionné, ainsi que l'utilisation de ces phases stationnaires chirales dans la séparation d'enantiomères.

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