C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/62 (2006.01) A61K 38/16 (2006.01) A61K 39/118 (2006.01) A61K 48/00 (2006.01) C07K 14/295 (2006.01) C07K 16/12 (2006.01) C07K 19/00 (2006.01) C12N 5/10 (2006.01) C12N 15/31 (2006.01) C12P 21/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/569 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2356057
The present invention provides a method fo nucleic acid, including DNA, immunization of a host, including humans, against disease caused by infection by a strain of Chlamydia, specifically C. pneumoniae, employing a vector containing a nucleotide sequence encoding an ATP/ADP translocase of a strain of Chlamydia pneumoniae and a promoter to effect expression of the ATP/ADP translocase gene in the host. Modifications are possible within the scope of this invention.
La présente invention concerne une méthode d'immunisation d'un hôte par acide nucléique (y compris l'ADN), notamment des sujets humains contre une maladie provoquée par une infection due à une souche de Chlamydia, spécifiquement C. pneumoniae, utilisant un vecteur contenant une séquence nucléotidique codant une ATP/ADP translocase d'une souche de Chlamydia pneumoniae ainsi qu'un promoteur pour provoquer l'expression du gène d'ATP/ADP translocase chez l'hôte. Des modifications sont possibles dans la portée de cette invention.
Dunn Pamela
Murdin Andrew D.
Oomen Raymond P.
Wang Joe
Aventis Pasteur Limited
Smart & Biggar
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