Chromatographic determination of p-glycoprotein reactive...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/00 (2006.01) C07K 16/00 (2006.01) C12P 7/00 (2006.01) C12P 29/00 (2006.01) G01N 33/537 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2376825

A flow chromatographic system with P-glycoprotein immobilized thereto is used in a method of identifying, isolating, and characterizing ligands that are reactive to P-glycoprotein.

L'invention concerne un procédé permettant d'identifier, d'isoler et de caractériser des ligands qui sont réactifs à la P-glycoprotéine. Ce procédé utilise un système de chromatographie liquide dans lequel de la P-glycoprotéine est immobilisée.

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