Chromogenic enzyme substrates

Details Chromogenic enzyme substrates Chromogenic enzyme substrates

C - Chemistry, Metallurgy

07

K

530/5.08, 150/15

C07K 5/083 (2006.01) C12Q 1/37 (2006.01) C12Q 1/56 (2006.01)

Patent

CA 1081212

ABSTRACT OF THE DISCLOSURE The present invention relates to novel tripeptide deerivatives of the basic formula H - A1 - A2 - A3 - NH - R wherein each A group is an amino acid and -NH-R is a group which, when split off under enzyme action, can be determined quantitatively, for example a nitro phenylamino group. These compounds find use as chromogenic substrates for the estimation of enzymes of the type serine proteases (EC 3.4.21).

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