Class iia histone deacetylase (hdac) substrate

Details Class iia histone deacetylase (hdac) substrate Class iia histone deacetylase (hdac) substrate

C - Chemistry, Metallurgy

12

N

C12N 9/14 (2006.01) C12Q 1/34 (2006.01)

Patent

CA 2621448

The present invention relates to the use of trifluoroacetylated lysine (Boc-L- Lys(.epsilon.- trifluoroacetyl)-MCA) as a substrate for histone deacetylases, specific for the class Ha subtype.

L'invention concerne l'utilisation de lysine trifluoroacétylée (Boc-L-Lys(e- trifluoroacétyl)-MCA) comme substrat des histones déacétylases, convenant plus précisément au sous-type classe IIa.

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