C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07K 7/04 (2006.01) C07K 14/47 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01) G01N 33/569 (2006.01)
Patent
CA 2087787
24 ABSTRACT CLONING AND CHARACTERIZATION OF A GENE, INDUCIBLE BY CYTOKINES The present invention relates to a previously unknown gene, apparently belonging to the pentaxin family, which is inducible by one or more cytokines, and whose expression is not limited to hepatocytes, the mRNA being abundant in cytokine-activated fibroblastic and endothelial cells, and the gene being strongly induced by TNF.alpha. and IL-1, but not IL-6 (the primary inducer of SAP and CRP), so that assaying the expression product may provide an independent indication of tissue stress in most tissue types.
Breviario Ferruccio
Dejana Elisabetta
Introna Martino
Legname Giuseppe
Mantovani Alberto
Breviario Ferruccio
Dejana Elisabetta
Introna Martino
Italfarmaco S.p.a.
Kirby Eades Gale Baker
LandOfFree
Cloning and characterization of a gene, inducible by cytokines does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Cloning and characterization of a gene, inducible by cytokines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cloning and characterization of a gene, inducible by cytokines will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1917550