C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/60 (2006.01) A61K 38/51 (2006.01) A61M 1/38 (2006.01) C07H 21/00 (2006.01) C07K 16/40 (2006.01) C12N 1/19 (2006.01) C12N 5/10 (2006.01) C12N 9/88 (2006.01) C12Q 1/68 (2006.01) G01N 33/564 (2006.01) G01N 33/573 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2103159
2103159 9220811 PCTABS00017 Human pancreatic islet cell glutamic acid decarboxylase (GAD), an autoantigen involved in the development of insulin-dependent diabetes mellitus (IDDM), has been cloned, sequenced and expressed by recombinant means. Recombinant human islet cell GAD polypeptides and antibodies specific to the GAD polypeptides can be used in methods of diagnosis and treatment, including use in immunoadsorptive therapy and the induction of immune tolerance.
Foster Donald C.
Grubin Catherine E.
Hagopian William
Karlsen Allen E.
Lernmark Ake
Fetherstonhaugh & Co.
The Board Of Regents Of The University Of Washington
Zymogenetics Inc.
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