Co-dominant genetic diagnosis test

Details Co-dominant genetic diagnosis test Co-dominant genetic diagnosis test

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2228694

A method for detecting the homozygous or heterozygous state of mutations assumed to be present in a nucleic acid by simultaneously using two primer pairs. The two different primer pairs lead to the production of amplified fragments of different sizes, and the number and quality of the amplified bands enables homozygous and heterozygous items to be distinguished on the basis of said mutation.

Méthode de détection de l'état homozygote ou hétérozygote de mutations présumées dans un acide nucléique faisant intervenir simultanément deux couples d'amorces. Les deux couples d'amorces différents conduisent à la production de fragments amplifiés de tailles différentes, le nombre et la qualité des bandes amplifiées permettant de distinguer les individus homozygotes et hétérozygotes vis-à-vis de ladite mutation.

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