B - Operations – Transporting – 05 – D
Patent
B - Operations, Transporting
05
D
B05D 1/40 (2006.01) A61K 9/00 (2006.01) A61L 31/08 (2006.01) A61L 31/16 (2006.01) A61M 37/00 (2006.01)
Patent
CA 2619452
The present invention is a transdermal delivery microprojection assembly that includes a microprojection member (12) secured to a retainer (22) adapted for use with an impact applicator wherein at least a portion of the microprojections extend beyond a plane formed by the end of the retainer. The configuration allows a biocompatible coating containing a biologically active agent to be applied to the microprojection member after it is mounted on the retainer. The present invention minimizes the number of manufacturing steps that must be carried out under aseptic conditions to maintain sterility of the assembly after the coating is applied to the microprojection member.
L'invention porte sur un dispositif d'administration transdermique à microprojections comportant un support (12) de microprojections se fixant à un rétenteur (22) s'utilisant avec un applicateur à impact, une partie au moins des microprojections s'étendant au delà d'un plan formé par l'extrémité du support. La configuration du dispositif permet d'enduire le support (12) une fois fixé au rétenteur d'un agent biologiquement actif. On réduit ainsi le nombre des étapes de fabrication devant être effectuées dans des conditions d'asepsie pour maintenir la stérilité du dispositif après l'enduisage du support de microprojections.
Donnelly Doran P.
Tong Ling-Kang
Trautman Joseph C.
Alza Corporation
Borden Ladner Gervais Llp
LandOfFree
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