Collagen wound healing matrices and process for their...

A - Human Necessities – 61 – L

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167/153, 167/327

A61L 27/00 (2006.01) A61K 38/39 (2006.01) A61L 27/24 (2006.01) A61L 27/54 (2006.01) A61F 2/00 (2006.01)

Patent

CA 1339007

Collagen implants that are useful as wound healing matrices are characterized by being formed of collagen fibrils that are not chemically cross-linked, and having a bulk density of 0.01 to 0.3 g/cm3 and a pore population in which at least about 80% of the pores have an average pore size of 35 to 250 microns. The implants are capable of promoting connective tissue deposition, angiogenesis, reepithelialization, and fibroplasia. The wound healing matrix also serves as an effective sustained delivery system for bioactive agents.

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