Combination of a macrolide t-cell immunomodulator and a...

Details Combination of a macrolide t-cell immunomodulator and a... Combination of a macrolide t-cell immunomodulator and a...

A - Human Necessities

61

K

A61K 31/593 (2006.01) A61K 31/453 (2006.01) A61P 1/00 (2006.01) A61P 17/00 (2006.01)

Patent

CA 2519096

Synergistic combinations of a macrolide T-cell immunomodulator or immunosuppressant such as 33-epichloro-33-desoxyascomycin and a calciferol such as calcipotriol or tacalcitol are provided, which are useful in particular in the treatment of dermatological diseases such as atopic dermatitis, acne and psoriasis, or of inflammatory bowel disease (IBD).

L'invention concerne des combinaisons synergistiques d'un immunomodulateur ou immunosuppresseur de lymphocyte T macrolide, tel que 33-épichloro-33-désoxyascomycine et d'un calciférol, tel que le calcipotriol ou le tacalcitol, utiles notamment dans le traitement de maladies dermatologiques, telles que la dermatite atopique, l'acné et le psoriasis ou d'une maladie intestinale inflammatoire (IBD).

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