A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/08 (2006.01) A61K 31/194 (2006.01) A61K 31/435 (2006.01) A61K 31/4422 (2006.01) A61K 45/06 (2006.01)
Patent
CA 2405559
The invention is a pharmaceutical composition comprising a carboxyalkylether of the formula (I) wherein R1, R2, R3, and R4 include alkyl, alkenyl, and alkynyl, m and n are integers from 2 to 9, Y1 and Y2 include COOH, CHO, tetrazole, COOR5 where R5 is alkyl, alkenyl, or alkynyl, or a pharmaceutically acceptable salt thereof, and an antihypertensive agent, said composition being useful for treating vascular diseases. The invention includes a method of treating hypertension comprising administering a carboxyalkylether.
L'invention concerne une composition pharmaceutique comprenant un carboxyalkyléther de la formule, dans laquelle R¿1?, R¿2?, R¿3? et R¿4? renferment alkyle, alcényle et alkynyle, m et n étant des entiers de 2 à 9. Y¿1? et Y¿2? renferment COOH, CHO, tétrazole, COOR¿5?, R¿5? étant alkyle, alcényle ou alkynyle ou un sel de ceux-ci pharmaceutiquement acceptable, ainsi qu'un agent antihypertenseur. Ladite composition permet de traiter des maladies vasculaires. L'invention porte également sur un procédé de traitement de l'hypertension consistant à administrer un carboxyalkyléther.
Auerbach Bruce Jeffrey
Hitchcock Karen Diane
Ryan Michael John
Sim & Mcburney
Warner-Lambert Company
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