C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/47 (2006.01) A61K 31/44 (2006.01) A61K 31/50 (2006.01) A61K 31/505 (2006.01) C07D 213/75 (2006.01) C07D 215/38 (2006.01) C07D 237/22 (2006.01) C07D 498/04 (2006.01)
Patent
CA 2513493
A composition, method and kit comprising a compound for the inhibition of the binding of .alpha.4.beta.1 integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin and other therapeutic compounds for the control or prevention of diseases states in which .alpha.4.beta.1 is involved.
L'invention concerne une composition, une méthode et un kit comprenant un composé destiné à inhiber la liaison de l'intégrine .alpha.¿4??¿1? à ses récepteurs, par exemple la VCAM-1 (molécule d'adhésion des cellules vasculaires) et la fibronectine, et d'autres composés thérapeutiques de traitement ou de prévention des états pathologiques associés à la .alpha.¿4??¿1?.
Aslanian Robert G.
Chapman Richard W.
Holland George
Kreutner William
Shih Neng-Yang
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Schering Corporation
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