Combination treatment for inhibiting bone loss

Details Combination treatment for inhibiting bone loss Combination treatment for inhibiting bone loss

A - Human Necessities

61

K

A61K 31/66 (2006.01) A61K 31/675 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2154414

The present invention provides a method for inhibiting bone loss comprising administering to a human in need thereof a first compound selected from 1) triarylethylenes; 2) 2,3-diaryl- 2H-1-benzopyrans, 3) 1-aminoalkyl-2-phenylindoles; 4) 2-phenyl- 3-aroylbenzothiophenes, 5) 1-substituted-2-aryl- dihydronaphthalenes; or 6) benzofurans, and a second compound being a bisphosphonate: or pharmaceutically acceptable salts and solvates thereof. Also encompassed by the invention are combination pharmaceutical formulations and salts.

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