C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/12 (2006.01) A61K 31/496 (2006.01) A61K 45/06 (2006.01) A61P 3/00 (2006.01) A61P 3/12 (2006.01) C07D 209/12 (2006.01) C07D 209/16 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 403/14 (2006.01) C07D 405/04 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 409/04 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01) C07D 413/04 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/04 (2006.01) C07D 417/12 (2006.01) C07D 471/04
Patent
CA 2413044
This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and mthod of use. In particular, the invention is converned with indoleoxoacetyl piperazine derivatives. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. Mor particularly, the present invention relates to the treatment of HIV and AIDS.
La présente invention concerne des composés possédant des propriétés médicamenteuses et bioactives, des compositions pharmaceutiques à base de ces composés et des techniques d'utilisation. Cette invention concerne en particulier des dérivés de piperazine indoleoxoacétyle. Ces composés possèdent une activité antivirale unique, qu'ils soient utilisés seuls ou en combinaison avec d'autres antiviraux, des anti-infectieux, des immunomodulateurs ou des inhibiteurs d'entrée du VIH. Cette invention concerne plus particulièrement le traitement du VIH et du sida.
Fang Haiquan
Meanwell Nicholas A.
Pearce Bradley C.
Qiu Zhilei
Wallace Owen B.
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
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