C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 21/08 (2006.01) A61K 39/00 (2006.01) C07K 14/705 (2006.01) C07K 16/30 (2006.01) C12N 5/28 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01)
Patent
CA 2058420
2058420 9014595 PCTABS00002 This invention provides the hybridoma designated F 33 (ATCC No. HB 10155) and the monoclonal antibody produced by it. This invention also provides a method of detecting the sensitivity of a malignant cell or tissue to alpha interferon therapy which comprises contacting a sample of the malignant cell or tissue with a monoclonal antibody which recognizes an epitope of gp 160 cell surface antigen under conditions such that an antibody-antigen complex is formed between the monoclonal antibody and the gp 160 cell surface antigen, if the antigen is present in the sample; and detecting any complex so formed, the absence of complex indicating that the malignant cell or tissue is sensitive to alpha interferon therapy.
Albino Anthony P.
Bander Neil H.
Nanus David M.
Pfeffer Lawrence M.
Albino Anthony P.
Bander Neil H.
Gowling Lafleur Henderson Llp
Nanus David M.
Pfeffer Lawrence M.
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