Composition comprising coagulation factor viii formulation,...

Details Composition comprising coagulation factor viii formulation,... Composition comprising coagulation factor viii formulation,...

A - Human Necessities

61

K

A61K 38/37 (2006.01) A61K 47/02 (2006.01) A61K 47/18 (2006.01) A61K 47/26 (2006.01) A61K 47/34 (2006.01) A61P 7/04 (2006.01)

Patent

CA 2124690

The present invention relates to novel composition comprising coagulation factor VIII and a non-ionic surfactant such as block copolymers, e.g. polyoxamers or polyoxyethylene (20) sorbitan fatty acid esters e.g. polysorbate 20 or polysorbate 80 as stabilizer. The composition can also comprise sodium chloride, calcium chloride, L-histidine and/or sugars or sugar alcohols. The invention also relates to the use of a non-ionic surfactant as stabilizer for a composition comprising coagulation factor VIII.

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