Compositions and methods comprising a ligand of chemerinr

Details Compositions and methods comprising a ligand of chemerinr Compositions and methods comprising a ligand of chemerinr

C - Chemistry, Metallurgy

07

K

C07K 7/00 (2006.01) C07K 14/47 (2006.01) C07K 14/575 (2006.01) C07K 16/18 (2006.01) C07K 16/28 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2499008

The present invention relates to a G-protein coupled receptor and a novel ligand therefor. The invention provides screeing assays for the identification of candidate compounds which modulate the activity of the G-protein coupled receptor, as well as assays useful for the diagnosis and treatment of a disease or disorder related to the dysregulation of G-protein coupled receptor signaling.

La présente invention concerne un récepteur couplé aux protéines G et un ligand destiné à ce récepteur. L'invention concerne également des dosages de criblage destinés à l'identification de composés candidats modulant l'activité du récepteur couplé aux protéines G, ainsi que des dosages servant au diagnostic et au traitement d'une maladie ou d'un trouble lié à la dysrégulation de la signalisation du récepteur couplé aux protéines G.

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