A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/50 (2006.01) A61K 31/485 (2006.01) A61P 25/04 (2006.01)
Patent
CA 2699172
Described herein are compositions comprising particles of poorly soluble drugs encapsulated by stabilizers. Further described are pharmaceutical compositions comprising such encapsulated compositions. Also described are methods of making such encapsulated particle compositions, and methods of making the corresponding pharmaceutical compositions. The encapsulated particle compositions described herein allow poorly soluble drugs to be administered with good bioavailability by routes that are non-invasive to patients, such as by oral administration.
L'invention décrit des compositions comprenant des particules de médicaments médiocrement solubles encapsulées par des agents de stabilisation. L'invention décrit en outre des compositions pharmaceutiques comprenant de telles compositions encapsulées. Elle décrit également des procédés de fabrication de telles compositions de particules encapsulées et des procédés de fabrication des compositions pharmaceutiques correspondantes. Les compositions de particules encapsulées décrites ici permettent une administration de médicaments médiocrement solubles avec une bonne biodisponibilité par des trajets qui sont non invasifs pour les patients, telle qu'une administration par voie orale.
Talton James D.
Mcfadden Fincham
Nanotherapeutics Inc
LandOfFree
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