Compositions and methods for removal of detergents

Details Compositions and methods for removal of detergents Compositions and methods for removal of detergents

G - Physics

01

N

8/113, 167/37, 2

G01N 33/569 (2006.01) B01F 17/00 (2006.01) C07C 323/14 (2006.01) C07K 1/32 (2006.01) C07K 14/22 (2006.01) C07K 14/295 (2006.01) G01N 33/68 (2006.01) G01N 33/92 (2006.01)

Patent

CA 1340353

Compounds having detergent properties are disclosed. When a modifying reagent is brought into contact with these compounds, the detergent properties are decreased. These compounds are useful, for example, as solubilizing agents for microbial antigens and/or antibodies and for reversibly wetting hydrophobic surfaces. Accordingly, methods are disclosed for increasing the hydrophilic properties of a material, such as a microbial antigen and/or antibody, the methods generally comprising the steps of contacting the material with the compound having detergent properties and a modifiable group, and modifying the compound with a modifying reagent. Kits are also disclosed for use in accordance with this methodology.

606510

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