C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 19/00 (2006.01) A61K 38/17 (2006.01) A61K 38/46 (2006.01) A61K 47/48 (2006.01) A61P 3/00 (2006.01) C07K 14/47 (2006.01) C12N 9/14 (2006.01)
Patent
CA 2400802
Methods and models for transporting agents across the blood brain barrier, the preparation of antibodies and antisense oligonucleotides, the preparation of experimental systems to study murine p97, the isolation of substances that modulate murine p97 expression and/or activity as well as the use of the murine p97 nucleic acid sequences and proteins and modulators thereof in diagnostic and therapeutic applications are described.
L'invention concerne des procédés et des modèles de transport d'agents à travers la barrière hémato-encéphalique, la préparation d'anticorps et d'oligonucléotides antisens, la préparation de systèmes expérimentaux pour l'étude de murine p97, l'isolation de substances qui modulent l'expression et/ou l'activité de murine p97 ainsi que l'utilisation des séquences d'acide nucléique de murine p97, de leurs protéines et de leurs modulateurs dans des applications diagnostiques et thérapeutiques.
Cheng Nick
Gagnier Liane
Jefferies Wilfred A.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
University Of British Columbia
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