A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/42 (2006.01) A61K 31/05 (2006.01) A61K 31/7088 (2006.01) A61K 47/18 (2006.01) A61K 47/48 (2006.01)
Patent
CA 2509365
The present invention relates to a pharmaceutical composition comprising a pharmaceutical agent and a pharmaceutically acceptable carrier, which carrier comprises a protein, for example, human serum albumin and/or deferoxamine. The human serum albumin is present in an amount effective to reduce one or more side effects associated with administration of the pharmaceutical composition. The invention also provides methods for reducing one or more side effects of administration of the pharmaceutical composition, methods for inhibiting microbial growth and oxidation in the pharmaceutical composition, and methods for enhancing transport and binding of a pharmaceutical agent to a cell.
La présente invention concerne une composition pharmaceutique renfermant un agent pharmaceutique et un excipient acceptable pharmaceutiquement qui contient une protéine, par exemple, de l'albumine de sérum humain et/ou de la deferoxamine. L'albumine de sérum humain est présente dans une quantité efficace afin de diminuer au moins un effet secondaire lié à l'administration de la composition pharmaceutique. Cette invention a également trait à des méthodes permettant de diminuer au moins un effet secondaire de l'administration de la composition pharmaceutique, à des méthodes d'inhibition de la croissance microbienne et de l'oxydation de la composition pharmaceutique, et à des méthodes d'amélioration de l'acheminement et de la liaison d'un agent pharmaceutique à une cellule.
Beals Grim Bridget
Ci Sherry Xiaopei
De Tapas
Desai Neil P.
Soon-Shiong Patrick
Abraxis Bioscience Llc
American Bioscience Inc.
Smart & Biggar
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