Compositions and methods of enhancing immune responses to...

A - Human Necessities – 61 – K

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A61K 39/112 (2006.01) A61K 35/74 (2006.01) A61P 31/04 (2006.01) A61P 37/04 (2006.01)

Patent

CA 2704457

Vaccines comprising fliC and CD 154 polypeptides and Salmonella enteritidis vaccine vectors comprising fliC polypeptides are provided. Also provided are methods of enhancing an immune response against flagellated bacteria and methods of reducing morbidity associated with infection with flagellated bacteria.

L'invention porte sur des vaccins comprenant des polypeptides fliC et CD 154 et sur des vecteurs de vaccin contre Salmonella enteritidis comprenant des polypeptides fliC. L'invention porte également sur des procédés d'amélioration d'une réponse immunitaire contre des bactéries flagellées et sur des procédés de réduction de la morbidité associée à une infection par des bactéries flagellées.

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