Compositions and their use in lowering intraocular pressure

A - Human Necessities – 61 – K

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A61K 31/415 (2006.01)

Patent

CA 2029657

Compounds of formula: (see formula I) where X is -CH2-, -CH(CH3)-, -CHR3-CH2- or -CR3=CH- and R1, R2 and R3, which can be the same or different, are each H or CH3 or a stereoisomer or pharmaceutically acceptable salt thereof, and pharmaceutical compositions containing them, are useful for lowering intraocular pressure in a mammal, e.g. in the treatment of glaucoma.

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