A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/00 (2006.01) A61K 9/107 (2006.01) A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61K 9/70 (2006.01) A61K 31/565 (2006.01)
Patent
CA 2558393
The present invention relates to pharmaceutical composition comprising steroidal drugs, such as drospirenone, in molecularly dispersed form. Preferably, the compositions are provided as solid, semi-solid or liquid forms, which in turn preferably are adapted for oral administration and preferably to be absorbed from the gastro-intestinal tract. Such compositions are found to have high bioavailability, good chemical stability, and fast in~- vitro dissolution release and can be produced under conditions, which do not require costly equipment or safety guards.
La présente invention concerne une composition pharmaceutique comprenant des médicaments stéroïdes, tels que de la drospirénone, sous forme moléculairement dispersée. De préférence, ces compositions se présentent sous forme solide, semi-solide ou liquide, et sont administrées par voie orale et absorbées à partir du tractus gastro-intestinal. Lesdites compositions présentent une biodisponibilité élevée, une bonne stabilité chimique et une rapide libération par dissolution in vitro, et peuvent être produites dans des conditions ne requérant pas de dispositifs de protection ou d'équipements coûteux.
Funke Adrian
Wagner Torsten
Bayer Schering Pharma Aktiengesellschaft
Marks & Clerk
Schering Aktiengesellschaft
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