Compositions for encapsulation and controlled release

A - Human Necessities – 01 – N

Patent

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Details

A01N 25/14 (2006.01) A61K 9/16 (2006.01) A61K 47/34 (2006.01) B01J 13/16 (2006.01)

Patent

CA 2534042

The invention comprises compositions and methods useful for encapsulation and controlled release of guest molecules, such as drugs. Compositions of the present invention comprise a matrix comprising molecules that are non- covalently crosslinked by multi-valent cations, wherein the molecules that are non-covalently crosslinked are non-polymeric, have more than one carboxy functional group, and have at least partial aromatic or heteroaromatic character. The compositions are characterized in that a guest molecule may be encapsulated within the matrix and subsequently released.

L'invention concerne des compositions et des procédés utiles pour l'encapsulation et la libération contrôlée de molécules hôtes, telles que des médicaments. Les compositions selon la présente invention sont constituées d'une matrice comprenant des molécules qui sont réticulées de manière non covalente par des cations multivalents, les molécules qui sont réticulées de manière non covalente étant non polymères, présentant plus d'un groupe fonctionnel carboxy et présentant au moins un caractère aromatique ou hétéroaromatique partiel. Lesdites compositions sont caractérisées en ce qu'une molécule hôte peut être encapsulée dans la matrice et libérée ultérieurement.

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