Compositions of iodoaniline derivatives in film-forming...

Details Compositions of iodoaniline derivatives in film-forming... Compositions of iodoaniline derivatives in film-forming...

A - Human Necessities

61

K

A61K 49/04 (2006.01)

Patent

CA 2114908

ABSTRACT Disclosed are x-ray contrast compositions for oral or retrograde examination of the gastrointestinal tract comprising a polymeric material capable of forming a coating on the gastrointestinal tract and an x-ray producing agent of the formula Image and methods for their use in diagnostic radiology of the gastrointestinal tract wherein Z = H, halo, C1-C20 alkyl, cycloalkyl, lower alkoxy, cyano, where the alkyl and cycloalkyl groups can be substituted with halogen or halo-lower-alkyl groups; R1 and R2 are independently C1-C25 alkyl, cycloalkyl, acetyl or halo-lower-alkyl, optionally substituted with halo, fluoro- lower-alkyl, aryl, lower-alkoxy, hydroxy, carboxy, lower- alkoxy carbonyl or lower-alkoxy-carbonyloxy; n is 1-5; y is 1-4; and x is 1 or 2 in a pharmaceutically acceptable carrier.

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