C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 295/108 (2006.01) A61K 31/4453 (2006.01)
Patent
CA 2685268
The present disclosure is directed to methods for providing tolperisone having extremely low levels of 4-MMPPO (2-methyl-1-(4-methylphenyl)-propenone), as well as related compositions. The invention further relates to methods of treating a subject with tolperisone under conditions that limit exposure of the subject to tolerable levels of 4-MMPPO, among other features.
La présente invention concerne des méthodes de production de tolperisone possédant des valeurs extrêmement faibles de 4-MMPPO (2-méthyl-1(4-méthylphényl)-propénone), ainsi que des compositions associées. L'invention concerne également des méthodes destinées au traitement d'un sujet à l'aide de tolperisone dans des conditions qui limitent l'exposition du sujet à des niveaux tolérables de 4-MMPPO, notamment.
Gaeta Federico
Gerdes Klaus
Gungl Jozsef
Kaelz Beate
Rothenburger Jan
Avigen Inc.
Gowling Lafleur Henderson Llp
Sanochemia Pharmazeutika Ag
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