C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 311/46 (2006.01) A61K 31/18 (2006.01) A61P 29/00 (2006.01) C07C 323/62 (2006.01) C07D 207/32 (2006.01) C07D 213/65 (2006.01) C07D 213/74 (2006.01) C07D 233/54 (2006.01) C07D 239/34 (2006.01) C07D 295/20 (2006.01) C07D 317/60 (2006.01)
Patent
CA 2648202
The present invention relates to compounds, particularly those of formula (I'), where R, R1, R2, R3, R4, x and z are as defined in the claims, useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
La présente invention concerne des composés utiles en tant qu'inhibiteurs de canaux sodiques sensibles à la tension. Elle concerne également des compositions pharmaceutiquement acceptables comprenant les composés de l'invention et des procédés d'utilisation des compositions dans le traitement de divers troubles.
Gonzalez Jesus III
Joshi Pramod
Krenitsky Paul
Termin Andreas
Wang Jian
Smart & Biggar
Vertex Pharmaceuticals Incorporated
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