C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/4745 (2006.01) A61P 1/00 (2006.01) A61P 9/00 (2006.01) A61P 13/02 (2006.01) A61P 25/00 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2728096
Compound of formula (I) in which R1, R2 and R3 are defined in the following description, and the pharmaceutically acceptable acid-addition or base-addition salts thereof. The invention also relates to a process and an intermediate for prepar-ing it, and to a pharmaceutical composition comprising it. The invention also relates to the use of a novel 2H-pyrrolo[3,4-c]quinoline compound for preparing a pharmaceutical composition that is active in the treatment of disturbances of the serotoninergic system.
L'invention porte sur un composé de formule (I) dans laquelle R1, R2 et R3 sont définis dans la description suivante, et les sels d'addition avec un acide ou d'addition avec une base, pharmaceutiquement acceptables, de ce composé. L'invention porte également sur un procédé et un intermédiaire pour préparer ce composé, et sur une composition pharmaceutique le comprenant. L'invention porte également sur l'utilisation d'un nouveau composé 2H-pyrrolo [3,4-c]quinoléine pour préparer une composition pharmaceutique qui est active dans le traitement de perturbations du système sérotoninergique.
Alisi Maria Alessandra
Cazzolla Nicola
Costi Roberta
Di Santo Roberto
Furlotti Guido
Aziende Chimiche Riunite Angelini Francesco A.c.r.a.f. S.p.a.
Riches Mckenzie & Herbert Llp
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