Compounds active at a novel site on receptor-operated...

C - Chemistry – Metallurgy – 07 – C

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C07C 211/29 (2006.01) A61K 31/135 (2006.01) A61K 31/136 (2006.01) A61K 31/137 (2006.01) A61K 31/138 (2006.01) A61K 31/155 (2006.01) A61K 31/165 (2006.01) A61K 31/38 (2006.01) A61K 31/381 (2006.01) A61K 31/40 (2006.01) A61K 31/44 (2006.01) A61K 31/4409 (2006.01) A61K 31/4462 (2006.01) A61K 31/4465 (2006.01) C07C 211/27 (2006.01) C07C 211/28 (2006.01) C07C 211/40 (2006.01) C07C 211/54 (2006.01) C07C 215/28 (2006.01) C07C 215/54 (2006.01) C07C 217/10 (2006.01) C07C 217/48 (2006.01) C07C 217/60 (2006.01) C07C 2

Patent

CA 2223978

Method and compositions for treating a patient having a neurological disease or disorder, such as stroke, head trauma, spinal cord injury, spinal cord ischemia, ischemia- or hypoxia-induced nerve cell damage, epilepsy, anxiety, neuropsychiatric or cognitive deficits due to ischemia or hypoxia such as those that frequency occur as a consequence of cardiac surgery under cardiopulmonary bypass, or neurodegenerative diseases such as Alzheimer's Disease, Huntington's Disease, Parkinson's Disease, or amytrophic lateral sclerosis (ALS).

L'invention concerne un procédé et des compositions s'utilisant pour traiter un patient atteint de troubles ou souffrant d'une pathologie à caractère neurologique, tels qu'accident vasculaire cérébral, traumatisme crânien, lésion ou ischémie médullaire, altération de cellules nerveuses induite par ischémie ou hypoxémie, épilepsie, anxiété, déficits neuropsychiatriques ou intellectuels inhérents à l'ischémie ou à l'hypoxémie, du type de ceux qui interviennent fréquemment suite à une intervention chirurgicale cardiaque avec circulation extracorporelle, ou maladies neurodégénératives telles que la maladie d'Alzheimer, la chorée de Huntington, la maladie de Parkinson ou la sclérose latérale amyotrophique (ALS).

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