Compounds and methods for inhibiting the interaction of bcl...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 207/16 (2006.01) A61K 31/402 (2006.01) A61K 31/426 (2006.01) A61K 31/445 (2006.01) A61K 31/5375 (2006.01) A61P 35/00 (2006.01) C07D 211/60 (2006.01) C07D 265/30 (2006.01) C07D 277/06 (2006.01)

Patent

CA 2633958

The present invention relates to heterocyclic compounds that bind to BcI proteins and inhibit BcI function, compositions comprising such compounds, and methods for treating and modulating disorders associated with hyperproliferation, such as cancer.

La présente invention concerne des composés hétérocycliques qui se lient aux protéines Bcl et inhibent la fonction des Bcl, ainsi que des compositions comprenant ces composés et des procédés de traitement et de modulation de troubles associés à une hyperprolifération tels que le cancer.

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