C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) A61K 39/118 (2006.01) C07K 14/295 (2006.01) C07K 19/00 (2006.01)
Patent
CA 2354232
Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
L'invention porte sur des composés et procédés pour le traitement et le diagnostic d'infections par le Chlamydia. Lesdits composés comportent des polypeptides comportant au moins une partie antigénique d'un antigène du Chlamydia et les séquences d'ADN codant pour lesdits polypeptides. L'invention porte également sur des préparations pharmaceutiques et des vaccins comportant lesdits polypeptides ou leurs séquences d'ADN ainsi que sur des anticorps agissant contre ces polypeptides. L'invention porte en outre sur des trousses de diagnostic contenant lesdits polypeptides ou leurs séquences d'ADN et sur un réactif de détection adéquat pouvant servir à détecter chez des patients ou dans des échantillons biologiques les infections par le Chlamydia.
Bhatia Ajay
Fling Steven P.
Jen Shyian
Probst Peter
Skeiky Yasir A. W.
Corixa Corporation
Gowling Lafleur Henderson Llp
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