Compounds and methods for use thereof in the treatment of...

C - Chemistry – Metallurgy – 07 – D

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C07D 235/30 (2006.01) A61K 31/4184 (2006.01) A61P 35/00 (2006.01) C07D 235/32 (2006.01)

Patent

CA 2422916

Benzimidole derivatives of structures (I, II and III) in which R is CO2R2 or CONHR2 and the substituents have the meaning given in the description and salts and prodrugs thereof are disclosed, together with methods for the treatment of cancers or viral infections in warm blooded animals by administration of these compounds. such compounds may be used in combination with a chemotherapeutic agent and/or a potentiator.

Cette invention concerne des dérivés du benzimidazole, des sels de ce composé et des promédicaments à base de ce composé ainsi que des méthodes de traitement du cancer et d'infections virales chez des animaux à sang chaud au moyen desdits composés. Ces composés peuvent être utilisés conjointement avec un agent chimiothérapeutique et/ou un agent de potentialisation.

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