C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 211/70 (2006.01) A61K 31/192 (2006.01) A61K 31/196 (2006.01) A61K 31/405 (2006.01) A61K 31/4178 (2006.01) A61K 31/4375 (2006.01) A61K 31/439 (2006.01) A61K 31/4425 (2006.01) A61K 31/4439 (2006.01) A61K 31/455 (2006.01) A61K 31/465 (2006.01) A61K 31/616 (2006.01) A61K 45/06 (2006.01) A61P 25/28 (2006.01) C07D 401/04 (2006.01)
Patent
CA 2439898
Chimeric compounds are disclosed which are covalent conjugates of reversible or irreversible cholinergic up-regulators and non-steroidal anti-inflammatory drugs (NSAIDs), methods for their synthesis and use thereof for treatment and/or prevention of central nervous system (CNS) disorders and diseases.
L'invention concerne des composants chimériques qui sont des conjugués covalents de médicaments anti-inflammatoires non-stéroïdiens et régulateurs positifs cholinergiques réversibles ou irréversibles (NSAID), des procédés pour leur synthèse et l'utilisation de ceux-ci dans le traitement et/ou la prévention des troubles et maladies du système nerveux central (CNS).
Adani Rachel
Amitai Gabriel
Meshulam Haim
Rabinovitz Ishai
Sod-Moriah Gali
Adani Rachel
Amitai Gabriel
Israel Institute For Biological Research
Meshulam Haim
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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