Compounds having effects on serotonin-related systems

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 401/12 (2006.01) A61K 31/40 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/55 (2006.01) C07D 209/08 (2006.01) C07D 401/10 (2006.01) C07D 401/14 (2006.01) C07D 403/10 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01) C07D 413/12 (2006.01) C07D 471/08 (2006.01) C07D 471/10 (2006.01) C07D 491/10 (2006.01) C07D 491/107 (2006.01) C07D 491/20 (2006.01) C07D 495/10 (2006.01) C07D 49

Patent

CA 2210220

A series of hetero-oxy alkanamines are effective pharmaceuticals for the treatment of conditions related to or affected by the reuptake of serotonin and by the serotonin 1A receptor. The compounds are particularly useful for alleviating the symptoms of nicotine and tobacco withdrawal, and for the treatment of depression and other conditions for which serotonin reuptake inhibitors are used.

L'invention porte sur une série d'hétéro-oxy alcanamines qui sont des spécialités pharmaceutiques efficaces dans le traitement de manifestations liées au recaptage de sérotonine et au récepteur de la sérotonine 1A ou influencées par ce processus et cette substance. Ces composés s'avèrent des plus utiles s'agissant d'atténuer les symptômes de sevrage de nicotine et de tabac ainsi que dans le cadre du traitement de la dépression et d'autres troubles pour lesquels il est fait appel à des inhibiteurs du recaptage de sérotonine.

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