C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/94 (2006.01) A61K 31/517 (2006.01) A61P 25/00 (2006.01) A61P 29/00 (2006.01) C07D 401/04 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 471/04 (2006.01) C07D 495/04 (2006.01)
Patent
CA 2554566
The present invention relates to compounds of formula (I) useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders. Wherein R1, R2, X1-X4, P, and ring A are as defined in the present application.
La présente invention concerne des composés de la formule I utiles comme inhibiteurs de canaux sodiques potentiel-dépendants. L'invention concerne également des compositions pharmaceutiquement tolérables contenant les composés de l'invention et les procédés d'utilisation de ces compositions dans le traitement de divers troubles. R1, R2, X1-X4, P, et le cycle A ont la définition donnée dans la présente demande.
Gonzalez Jesus E. III
Martinborough Esther
Neubert Timothy D.
Termin Andreas P.
Wang Jian
Smart & Biggar
Vertex Pharmaceuticals Incorporated
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