Conjugates of hydroxyalkyl starch and g-csf

Details Conjugates of hydroxyalkyl starch and g-csf Conjugates of hydroxyalkyl starch and g-csf

A - Human Necessities

61

K

A61K 47/48 (2006.01)

Patent

CA 2534418

The present invention relates to conjugates of hydroxyalkyl starch and a granulocyte colony stimulating factor protein (G-CSF) wherein these conjugates are formed by a covalent linkage between the hydroxyalkyl starch or a derivative of the hydroxyalkyl starch and the protein. The present invention also relates to the methods of producing these conjugates and the use of these conjugates.

La présente invention concerne des conjugués d'amidon hydroxyalkylé et d'une protéine facteur stimulant les colonies de granulocytes (G-CSF), lesdits conjugués étant formés par une liaison covalente entre l'amidon hydroxyalkylé ou un dérivé de ce dernier et la protéine. Ladite invention concerne également des procédés pour produire ces conjugués et l'utilisation de ces derniers.

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