Connective tissue growth factor-3

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/18 (2006.01) A61K 38/18 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) C07H 17/00 (2006.01) C07K 14/475 (2006.01) C07K 16/22 (2006.01) C12N 5/00 (2006.01) C12N 15/00 (2006.01) C12N 15/10 (2006.01) C12N 15/66 (2006.01) C12P 21/06 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2270908

The present invention relates to a novel connective tissue growth factor-3 protein which is a member of the growth factor superfamily. In particular, isolated nucleic acid molecules are provided encoding the human connective tissue growth factor-3 protein. Connective tissue growth factor-3 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. Also provided are diagnostic and therapeutic methods for detecting and treating connective tissue related disorders.

La présente invention concerne une nouvelle protéine agissant comme facteur de croissance 3 du tissu conjonctif, qui fait partie de la superfamille des facteurs de croissance. L'invention concerne en particulier des molécules d'acides nucléiques isolés, codant la protéine agissant comme facteur de croissance 3 du tissu conjonctif. L'invention concerne également des polypeptides agissant comme facteur de croissance 3 du tissu conjonctif, ainsi que des vecteurs, cellules hôtes et méthodes de recombinaison pour les produire. L'invention concerne en outre des méthodes diagnostiques et thérapeutiques pour détecter et traiter des troubles liés au tissu conjonctif.

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