Constant length signatures for parallel sequencing of...

Details Constant length signatures for parallel sequencing of... Constant length signatures for parallel sequencing of...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C12N 15/10 (2006.01)

Patent

CA 2482425

Methods are disclosed for producing solid phase cloned libraries of ligonucleotide tag-DNA signature sequence constructs, in which the DNA signature components are all of the same length. Such libraries are especially useful for large-scale parallel sequencing of DNA signature sequences prepared from a source population, such as mRNA or genomic DNA.

L'invention porte sur des procédés d'élaboration de bibliothèques clonées en phase solide de constructs de séquences de signatures de marqueurs d'oligonucléotides d'ADN dans lesquels les signatures d'ADN sont d'égale longueur. Lesdites bibliothèques sont particulièrement utiles pour le séquençage en parallèle à grande échelle de séquences de signatures d'ADN préparées à partir de populations source telles que des ARNm ou des ADN de génomes.

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