Contrast media

Details Contrast media Contrast media

A - Human Necessities

61

K

A61K 49/00 (2006.01) A61K 9/14 (2006.01) A61K 49/04 (2006.01) A61K 49/18 (2006.01)

Patent

CA 2242647

The invention relates to MR contrast media containing composite nanoparticles, preferably comprising a superparamagnetic iron oxide core provided with a coating comprising an oxidatively cleaved starch coating optionally together with a functionalized polyalkyleneoxide which serves to prolong blood residence.

L'invention se rapporte à un milieu de contraste pour imagerie par résonance magnétique, qui contient des nanoparticules composites, lesdites particules comportant de préférence un noyau d'oxyde de fer superparamagnétique recouvert d'un enrobage d'amidon scindé par oxydation, éventuellement associé à un polyalkylèneoxyde servant à allonger la durée de séjour du milieu de contraste dans le sang.

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