A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/00 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 47/34 (2006.01) A61K 9/14 (2006.01)
Patent
CA 2504608
Methods and compositions for systemically or locally administering a beneficialagent to a subject are described, and include, for example, depot gel compositions that can be injected into a desired location and which can provide controlled release of @beneficial agent over a prolonged duration of time. The compositions include a biocompatiNe polymer, a biocompatible solvent having low water miscibility that forms a viscous gel with the polymer and limits water uptake by the implant, and a beneficial agent.
L'invention concerne des procédés et des compositions permettant d'administrer systématiquement ou localement un agent utile à un patient. L'invention concerne notamment des compositions de gel de dépôt qui peuvent être injectées à un emplacement souhaité et qui peuvent effectuer une administration contrôlée d'agents utiles pendant une durée prolongée. Ces compositions comprennent un polymère biocompatible, un solvant biocompatible présentant une miscibilité à l'eau faible qui forme un gel visqueux avec le polymère et qui limite l'absorption d'eau par l'implant et un agent utile.
Bannister Roy
Chen Guohua
Houston Paul
Kameda Teresa
Kleiner Lothar
Alza Corporation
Durect Corporation
Smart & Biggar
LandOfFree
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