Crohn disease susceptibility gene

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61K 45/00 (2006.01) A61K 48/00 (2006.01) A61P 1/00 (2006.01) C07H 21/00 (2006.01) C07K 14/47 (2006.01) C12Q 1/68 (2006.01) C40B 30/04 (2006.01) C40B 40/06 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2658563

The present invention relates to the ATG16l1 gene and genetic variants associated with Crohn's disease. In particular, the invention relates to the fields of pharmacogenomics, diagnostics, patient therapy and the use of genetic haplotype information to predict an individual's susceptibility to Crohn's disease and/or their response to a particular drug or drugs.

La présente invention concerne le gène ATG1611 et les variants génétiques associés à la maladie de Crohn. En particulier, l'invention concerne les domaines de pharmacogénomique, de diagnostic, de thérapie de patients et l'utilisation d'information d'haplotype génétique pour prédire la susceptibilité d'un sujet à la maladie de Crohn et/ou sa réaction à un médicament ou des médicaments particulier(s).

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