C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/475 (2006.01) C07K 14/71 (2006.01) C07K 14/82 (2006.01)
Patent
CA 2500288
More particularly, the present invention relates to the crystal structure of the ErbB2, in particular the crystal structure of an extracellular portion of ErbB2 and to methods of using the crystal and related structural information to screen for and design compounds that interact with ErbB2, or variants of thereof.
La présente invention se rapporte plus particulièrement à la structure cristalline de ErbB2, notamment à la structure cristalline d'une partie extracellulaire de ErbB2. Cette invention concerne également des procédés d'utilisation du cristal et des informations de structure associées afin de cribler et de mettre au point des composés qui interagissent avec ErbB2 ou avec des variants de ErbB2.
Adams Timothy Edward
Burgess Antony Wilkes
Elleman Thomas Charles
Garrett Thomas Peter John
Jorissen Robert Nicholas
Commonwealth Scientific And Industrial Research Organisation
Ludwig Institute For Cancer Research
Smart & Biggar
Walter And Eliza Hall Institute Of Medical Research
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