Crystal structure of phosphodiesterase 5 and use thereof

Details Crystal structure of phosphodiesterase 5 and use thereof Crystal structure of phosphodiesterase 5 and use thereof

C - Chemistry, Metallurgy

12

N

C12N 9/16 (2006.01) A61K 31/00 (2006.01) C12Q 1/44 (2006.01) G01N 33/58 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2478059

The present invention relates , inter alia to the crystal structures of a phosphodiesterase 5 (PDE5) and PDE5/PDE5 ligand complex and their uses in identifying PDE5 ligands, including PDE5 inhibitor compounds. The present invention also relates to methods of identifying such PDE5 inhibitor compounds and their medical use. Also contemplated by the present invention are crystals of PDE5/PDE5 inhibitor complexes.

L'invention concerne notamment les structures cristallines d'une phosphodiestérase 5 (PDE5) et d'un complexe de ligands PDE5/PDE5 ainsi que leurs utilisations dans l'identification des ligands PDE5, notamment des composés inhibiteurs PDE5. L'invention concerne également des méthodes permettant d'identifier lesdits composés inhibiteurs PDE5 ainsi que leur utilisation médicale. L'invention concerne également des cristaux de complexes d'inhibiteurs PDE5/PDE5.

Affiliated with

Also associated with

Rating

Crystal structure of phosphodiesterase 5 and use thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Crystal structure of phosphodiesterase 5 and use thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Crystal structure of phosphodiesterase 5 and use thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2022303