Crystalline acid addition salts of diastereomerically pure...

Details Crystalline acid addition salts of diastereomerically pure... Crystalline acid addition salts of diastereomerically pure...

C - Chemistry, Metallurgy

07

D

C07D 501/34 (2006.01) A61K 31/545 (2006.01) C07D 501/00 (2006.01)

Patent

CA 2069200

The invention relates to crystalline acid addition salt of the two diastereomers of the 1-(2,2-dimethylpropionyl- oxy)-ethyl- 3-cephem-4-carboxylate of the general formula II (see formula I) in which X is the anion of a physiologically acceptable, mono- or polybasic, inorganic or organic acid and the group =N-OH is in the syn-position, pharmaceutical formulations which are active against bacterial infec- tions and contain such cephem derivatives, processes for the preparation of the cephem derivatives and the use of the cephem derivatives for combating bacterial infections.

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