C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 5/072 (2006.01) A61K 38/05 (2006.01) A61P 17/06 (2006.01) C07K 1/00 (2006.01) C07K 1/14 (2006.01)
Patent
CA 2569204
A process for making pure crystalline D-isoglutamyl-D-tryptophan is provided which includes the step of deprotecting essentially pure N-tert-butoxycarbonyl-D- isoglutamyl-D-tryptophan or its diester to yield essentially pure D- isoglutamyl-D- tryptophan. A process is also provided for the preparation of pure mono ammonium salt of D-isoglutamyl-D-tryptophan from essentially pure N-tert-butoxycarbonyl- D- isoglutamyl-D-tryptophan. D-isoglutamyl-D-tryptophan, ammonium salt (1:1) is a stable pharmaceutical solid.
Leung-Toung Regis
N'zemba Blaise
Tam Tim
Wang Yingsheng
Yu Lily
Apotex Technologies Inc.
Mckinnon Graham J.k.
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